In what could be a big blow to the Jets, defensive lineman Quinnen Williams left Sunday’s game against the Bills in Orchard Park with a calf injury.

Williams walked gingerly off the field in the middle of the second quarter and was ruled out for the rest of the game after halftime.

The 25-year-old already had two sacks on Josh Allen in the game, bringing him to 11 for the season to extend his career-high. Williams, the No. 3 overall pick in the 2019 NFL Draft, is under contract through 2023 on his fifth-year option, after which he can become a free agent.

Earlier in Sunday’s game, Jets wide receiver Corey Davis was ruled out for the rest of the game after suffering a head injury in the first quarter. Davis left the game after making a 15-yard catch.

The 27-year-old wideout missed three games earlier this season with a knee injury, returning in Week 12 against the Bears to make one catch for nine yards. Last week against the Vikings, Davis had five catches on 10 targets for 85 yards.

Behind Garrett Wilson, the Jets have Elijah Moore, Braxton Berrios, and Denzel Mims at wide receiver.

Davis is in the second season of a three-year, $37.5 million contract he signed with the Jets in 2021. Over his first nine games this season, Davis had 25 catches for 445 yards receiving and two touchdowns. Last season, he had 34 catches for 492 yards and four touchdowns in nine games; core muscle surgery ended his 2021 campaign last December.

The Jets also had an injury scare with quarterback Mike White in the second quarter after he took a huge hit from Ed Oliver, but he returned to the game after Joe Flacco took over for two plays.