The New Opening for The Apothecary Diaries Season 2 Has Been Released

The TOHO animation YouTube channel has revealed the new opening animation for The Apothecary Diaries Season 2’s second cour ahead of the new episode’s premiere.

Set to Mrs. GREEN APPLE‘s “Kusushiki,” the season’s second opening features a mask motif, several first-person shots, and a dash of stylized visuals between stills of the cast. 

The Apothecary Diaries Season 2 premiered in Japan on January 10, 2025. Its premise reads:

When a favored concubine becomes pregnant, Maomao is put to the test as her food taster. She must keep her wits sharp, not only to protect the concubine but also against rising dangers in the palace. A new concubine with powerful ties, an unsolved attempt at Jinshi’s life, and a foreign envoy with impossible demands hint at a grand conspiracy poised to engulf the empire.

The anime is based on the Shufunotomo-published light novel series written by Natsu Hyuga and illustrated by Toko Shino. The light novels, which are published under the Hero Bunko imprint, began in 2014 and have 15 volumes as of March 2024. J-Novel Club’s synopsis reads:

In the East is a land ruled by an emperor, whose consorts and serving women live in a sprawling complex known as the hougong, the rear palace. Maomao, an unassuming girl raised in an unassuming town by her apothecary father, never imagined the rear palace would have anything to do with her—until she was kidnapped and sold into service there. Though she looks ordinary, Maomao has a quick wit, a sharp mind, and an extensive knowledge of medicine. That’s her secret, until she encounters a resident of the palace at least as perceptive as she is: the head eunuch, Jinshi. He sees through Maomao’s façade and makes her a lady-in-waiting to none other than the Emperor’s favorite consort… so she can taste the lady’s food for poison! At her lady’s side, Maomao starts to learn about everything that goes on in the rear palace—not all of it seemly. Can she ever lead a quiet life, or will her powers of deduction and insatiable curiosity bring her ever more adventures, and ever more dangers?

The Apothecary Diaries was originally a web novel that debuted on Shousetsuka ni Narou in 2011. The light novel series has two manga adaptations, one published by Square Enix and the other by Shogakukan. 

Series staff (reprising Season 1 role unless stated otherwise)

• Chief director and series composer: Norihiro Naganuma (Season 1 director and series composer) 
• Director: Akinori Fudesaka (Season 1 assistant director)
• Assistant director: Ko Nakagawa (Season 1 Episode 6, 13, and 19 storyboard artist and director, Episode 24 director)
• Character designer: Yukiko Nakatani 
• Color designer: Misato Aida 
• Background art director: Katsumi Takao
• Compositing director: Mayo Suzuki (The Apothecary Diaries project PV)
• Music composer: Alisa Okehazama 
• Music composer: Kevin Penkin 
• Music composer: Satoru Kosaki 
• Animation production: TOHO animation STUDIO and OLM

Cast

• Aoi Yuki as Maomao 
• Takeo Otsuka as Jinshi

Source: TOHO animation YouTube channel