Lieutenant Gov. Brian Benjamin resigned Tuesday evening just hours after he was indicted by federal prosecutors in Manhattan on a five corruption charges that alleged he attempted to trade a state grant for campaign contributions.

“I have accepted Brian Benjamin’s resignation effective immediately. While the legal process plays out, it is clear to both of us that he cannot continue to serve as Lieutenant Governor,” Gov. Kathy Hochul said.

“New Yorkers deserve absolute confidence in their government, and I will continue working every day to deliver for them,” she added.

Hochul — who picked Benjamin as her running mate last year — announced his departure after spending much of the day dodging questions about his arrest Tuesday morning.

However, the Harlem politician’s name will likely remain on the ballot for the primary as the deadline for withdrawing his candidacy passed in February.

Benjamin’s indictment and resignation may offer Hochul’s Democratic opponents a new opening in their bid to unseat her state’s June 28 primary, a contest the governor appeared to have largely sewn up after Attorney General Letitia James ended her campaign in December.