Bryson DeChambeau has been plagued by injuries this year but played in last week’s Masters anyway, against his doctor’s orders. Now it appears he is in danger of missing the year’s second major — next month’s PGA Championship — altogether.

The 28-year-old was scheduled to compete this week in a Professional Long Drivers Association event in Florida but pulled out of the competition and will instead undergo surgery on his left hand on Thursday, his agent confirmed to The Post on Wednesday.

“We look forward to a smooth recovery and rehab process,” DeChambeau’s agent, Brett Falkoff, said in a text. “Bryson looks forward to returning as soon as he is cleared to do so.”

Sports Illustrated was first to report the news.

Last month, DeChambeau revealed he had suffered a fractured hamate bone in his left hand and a torn labrum in his left hip. He also said he hurt the hand playing ping-pong at the Saudi International in early February.

When DeChambeau did return to playing after nearly two months, he didn’t make it out of pool play at the WGC-Dell Technologies Match Play. Then he missed the cut each of the following two weeks, at the Valero Texas Open and the Masters, where he shot 76-80.

“I’m probably around 80 percent right now,” he said at Augusta National before teeing it up in the tournament. “I can’t go all out. I can’t do any speed training sessions. I can’t practice for excessive hours, like I have to figure stuff out.”

DeChambeau, who won the 2020 U.S. Open at Winged Foot, has made just six worldwide starts so far in 2022. His best finish was a tie for 25th at the Sentry Tournament of Champions in January, though that tournament doesn’t have a cut and featured just 38 players in the field. He then missed the cut at the Farmers Insurance Open, withdrew from the Saudi International and didn’t play again for seven more weeks.

When DeChambeau will tee it up next is unknown. The PGA Championship will take place May 19-22 at Southern Hills in Tulsa, Oklahoma.