GSK on Friday put out a statement saying there’s no link between a withdrawn heartburn medication and cancer, helping to stem a slide in its stock that has wiped out billions of dollars in valuation from leading drugmakers.
“The overwhelming weight of the scientific evidence supports the conclusion that there is no increased cancer risk associated with the use of ranitidine. Suggestions to the contrary are therefore inconsistent with the science, and GSK will vigorously defend itself against all meritless claims alleging otherwise,” the U.K. drugmaker said, referring to the scientific name for Zantac.
GSK
GSK,
+3.67%
GSK,
-6.71%
rose 3% on Friday, but its shares have slumped 14% this week, its worst performance since the 2008 financial crisis.
Ahead of trials that are set to begin on Aug. 22, GSK said both the U.S. Food and Drug Administration as well as the European Medicines Agency have concluded there’s no evidence of a causal association between ranitidine therapy and the development of cancer in patients.
The GSK statement doesn’t reveal any new findings. The FDA findings were dated Nov. 2019 and June 2021, and the EMA review is from Sept. 2020. It mirrors comments from Sanofi, which also marketed the drug.
The FDA in 2019 recalled Zantac after testing showed it produced high levels of a cancer-causing substance.
GSK said it has been named as a defendant in 3,000 filed personal injury cases, and there are also cases in Canada and Israel.
GSK said it served its recent spinoff, Haleon, with notice of potential claims, though it said it isn’t clear the degree to which indemnities will limit or eliminate liability. Haleon
HLN,
+1.81%
HLN,
-3.38%,
whose London-listed stock has dropped 14% this week, has said it isn’t a party to any Zantac claim, and never marketed it in any form in the U.S.
Sanofi
SAN,
+1.00%
SNY,
-3.94%
shares also have dropped 13% this week. Analysts at Deutsche Bank upgraded the stock to hold from sell, saying the slide in the stock made a sell recommendation at this point “egregious.”
Pfizer
PFE,
-3.32%
also has been the subject of lawsuits but fallen a modest 2% this week. Privately held Boehringer Ingelheim is also a defendant.
