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#Getting realistic about the coronavirus death rate

#Getting realistic about the coronavirus death rate

June 25, 2020 | 8:25pm

With coronavirus infections rising again across the nation, the question of just how lethal the ­virus is has become more crucial than ever.

Early in the epidemic, public-health experts feared the virus might kill up to 2 percent of those infected, potentially causing millions of deaths in the United States and tens of millions worldwide. Those terrifying estimates prompted the lockdowns that have done incalculable harm to the economy, shattered small businesses and left children traumatized and untold numbers suffering from brutal isolation.

But we now know much more about the virus. And we know its lethality is lower than we originally feared — and highly concentrated in the very elderly and people with serious health problems.

In fact, the Centers for Disease Control and Prevention ­esti­mated in May that the coronavirus kills about 0.26 percent of the people it infects, about 1 in 400 people. New estimates from Sweden suggest that only 1 in 10,000 people under 50 will die from the virus, compared to 1 in 14 of people over 80 and 1 in 6 of those over 90.

Estimates for the coronavirus’ lethality have fallen so sharply because calculating the ­so-called infection fatality rate requires scientists and physicians to know both the total number of deaths and the total number of people infected.

Tracking deaths is relatively easy. But tracking infections can be tough. Many people who are infected with respiratory ­viruses like influenza or the novel coronavirus have only mild symptoms or none. They may never be tested or even know they are infected.

Thus, in the early stages of an epidemic, scientists must guess at the number of mild and hidden infections.

Probably the best way to discover the real number is through antibody tests, which measure how many people have already been infected and recovered — even if they never had symptoms.

Unlike some other countries, the United States still hasn’t completed a national random antibody study — yet another way in which our public-health establishment has failed to get the data we need to make good decisions about lockdowns. But some counties, states and countries have.

Those studies consistently show that far more people have been infected with and recovered from the coronavirus than suggested by data from tests that only measure current infections. Tests of municipal sewage systems — measuring the virus’ genetic signature in wastewater — have had similar findings.

Nearly all the studies find between 10 and 100 times the number of total infections as reported infections, with the average somewhere around 20 to 25 times.

In other words, while the CDC reports 2.34 million Americans have been infected with the coronavirus, the actual number of infected and recovered people may be closer to 50 million. (CDC Director Robert Redfield told journalists Thursday that the number of cases may be 10 times higher than the earlier 2.34 million.)

Thus, the death rate, which would be 5.2 percent based on that 2.34 million figure, is actually more like one-20th as high — or 0.26 percent.

To be sure, these estimates still have some uncertainty. The ­actual figure could be as low as 0.1 percent or as high as 0.4 to 0.5 percent, though treatment advances should mean it will trend lower over time. Even at 0.26 percent, the rate is still significantly higher than influenza most years, more comparable to a bad flu strain like the 1968 Hong Kong flu.

But it is far lower than we initially thought — a fact that should be cause for celebration.

Instead, some media outlets insist on using the out-of-date estimates that are much higher. For example, an ESPN article this week said public discussions about reopening the National Football League were “ignoring a mortality rate that has been estimated at 1.4 percent.” That figure is more than five times the CDC’s best estimate. Even more jarring, it is more than 100 times the actual risk to people in their 20s and 30s — the age range for nearly all NFL players.

Using those overstated estimates is a recipe for panic, bad public policy — and continued lockdowns that may delay to ­return to normality.

Let’s hope that isn’t the reason people in the media are using them.

Alex Berenson, a former New York Times reporter, is the author of “Unreported Truths About COVID-19 and Lockdowns: Part 1, Introduction and Death Counts and Estimates,” available on Amazon. This essay is adapted from that booklet. Twitter: @AlexBerenson

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