Two-time failed presidential candidate Hillary Clinton has insisted she will never again seek the highest office in the land.

The former secretary of state and senator from New York was asked by “CBS Evening News” anchor Norah O’Donnell about ever-present rumors that she will try one more time to avenge her historic losses to Barack Obama in 2008 and Donald Trump in 2016.

“No — no,” the 74-year-old Clinton replied without hesitation when asked if she would “ever run for president again.”

“But I’m gonna do everything I can to make sure that we have a president who respects our democracy and the rule of law and upholds our institutions,” she added in a clear shot at Trump.

Asked by O’Donnell how that would work “if Donald Trump runs again,” Clinton said bluntly, “He should be soundly defeated.”

“It should start in the Republican Party – grow a backbone! Stand up to this guy!” she added. “And heaven forbid if he gets the nomination, he needs to be defeated roundly and sent back to Mar-a-Lago.”

Clinton also insisted to O’Donnell that the FBI raid on Trump’s Palm Beach, Fla. home Aug. 8 was “a very different situation” to the months-long investigation into her use of a personal email server while serving as America’s top diplomat.

“I was cleared and [former FBI Director James Comey] just kept talking and talking,” she said. “And then came up with a new reason to talk some more 10 days before the election.”

“There’s no doubt at all that he impacted very negatively my chances of winning,” Clinton complained.

“It was in the middle of an election, there was nothing there and the guy never shut up.

“So I think it’s a really different comparison to what’s going on [with Trump], when it appears that the Justice Department [and] the FBI have been incredibly patient, quiet, careful until they finally — apparently — thought that national security was at stake,” she said.

Comey famously announced in the summer of 2016 that Clinton had been “extremely careless” in handling sensitive information, but added that despite “evidence of potential violations” of federal law, “our judgment is that no reasonable prosecutor” would bring a case against the former first lady.

Clinton has been the subject of ongoing rumors that she would run again after making a series of high-profile appearances.

However, she has insisted she would back President Biden if he were to run for a second term in 2024.